BDBM50252047 (2S,4S)-4-(2-Hydroxy-2-oxoethyl)glutamic Acid::(2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid::CHEMBL479797

SMILES N[C@@H](C[C@@H](CC(O)=O)C(O)=O)C(O)=O

InChI Key InChIKey=QUHCPZVRCOASQB-UHFFFAOYSA-N

Data  3 KI  3 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50252047   

TargetMetabotropic glutamate receptor 7(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human mGlu7 receptor expressed in HEK293 assessed as inhibition of forskolin stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells assessed as inhibition of forskolin stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu1 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu5 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu3 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of glutamate-induced depolarization in human EAAT3 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of glutamate-induced depolarization in human EAAT1 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of glutamate-induced depolarization in human EAAT2 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataKi: >3.00E+6nMAssay Description:Inhibition of [3H]D-Asp uptake at EAAT1 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252047((2S,4S)-4-aminobutane-1,2,4-tricarboxylic acid | (...)
Affinity DataKi: >3.00E+6nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed