BDBM50252071 3-((dimethylamino)methyl)-4-(4-(trifluoromethyl)phenylthio)benzenesulfonamide::CHEMBL500629

SMILES CN(C)Cc1cc(ccc1Sc1ccc(cc1)C(F)(F)F)S(N)(=O)=O

InChI Key InChIKey=JMOZPPPEEGAIOO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252071   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252071(3-((dimethylamino)methyl)-4-(4-(trifluoromethyl)ph...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252071(3-((dimethylamino)methyl)-4-(4-(trifluoromethyl)ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252071(3-((dimethylamino)methyl)-4-(4-(trifluoromethyl)ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed