BDBM50252168 3-((dimethylamino)methyl)-4-(4-(trifluoromethoxy)phenoxy)benzamide::CHEMBL481695

SMILES CN(C)Cc1cc(ccc1Oc1ccc(OC(F)(F)F)cc1)C(N)=O

InChI Key InChIKey=MOEZDBSMUWWXGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252168   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252168(3-((dimethylamino)methyl)-4-(4-(trifluoromethoxy)p...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252168(3-((dimethylamino)methyl)-4-(4-(trifluoromethoxy)p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252168(3-((dimethylamino)methyl)-4-(4-(trifluoromethoxy)p...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed