BDBM50252171 CHEMBL481697::N-(3-((dimethylamino)methyl)-4-(4-(trifluoromethoxy)phenoxy)benzyl)methanesulfonamide

SMILES CN(C)Cc1cc(CNS(C)(=O)=O)ccc1Oc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=USDWPOAZUSPDGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252171   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252171(N-(3-((dimethylamino)methyl)-4-(4-(trifluoromethox...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252171(N-(3-((dimethylamino)methyl)-4-(4-(trifluoromethox...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252171(N-(3-((dimethylamino)methyl)-4-(4-(trifluoromethox...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed