BDBM50252172 5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide::CHEMBL443964

SMILES CNC1CCC(c2ccc(Cl)c(Cl)c2)c2ccc(cc12)S(N)(=O)=O

InChI Key InChIKey=HGBGXSPIBLZGHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252172   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252172(5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tet...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252172(5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tet...)
Affinity DataIC50: 90nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252172(5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tet...)
Affinity DataIC50: 770nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed