BDBM50252245 (2R)-1-{[3-(4-ethylpiperazin-1-yl)phenyl]sulfonyl}-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazine::CHEMBL520590

SMILES CCN1CCN(CC1)c1cccc(c1)S(=O)(=O)N1CCN(C[C@H]1C)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=IYDCKVDSXPCRNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252245   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252245((2R)-1-{[3-(4-ethylpiperazin-1-yl)phenyl]sulfonyl}...)
Affinity DataIC50: 29nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252245((2R)-1-{[3-(4-ethylpiperazin-1-yl)phenyl]sulfonyl}...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252245((2R)-1-{[3-(4-ethylpiperazin-1-yl)phenyl]sulfonyl}...)
Affinity DataIC50: 45nMAssay Description:Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed