BDBM50252247 CHEMBL517997::Ethyl 2-oxo-2-[5-((S)-1-phenyl-ethylcarbamoyl)-thiophen-2-yl]-ethyl Trithiocarbonate

SMILES CCSC(=S)SCC(=O)c1ccc(s1)C(=O)N[C@@H](C)c1ccccc1

InChI Key InChIKey=PHRZHWJJTXWEKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252247   

TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252247(Ethyl 2-oxo-2-[5-((S)-1-phenyl-ethylcarbamoyl)-thi...)
Affinity DataIC50: 497nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252247(Ethyl 2-oxo-2-[5-((S)-1-phenyl-ethylcarbamoyl)-thi...)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed