BDBM50252319 CHEMBL479602::Ethyl 2-oxo-2-{5-[(2-Phenoxy-ethylcarbamoyl)-methyl]-thiophen-2-yl}-ethyl Trithiocarbonate

SMILES CCSC(=S)SCC(=O)c1ccc(CC(=O)NCCOc2ccccc2)s1

InChI Key InChIKey=WJUOYRHRYZIBNE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252319   

TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252319(Ethyl 2-oxo-2-{5-[(2-Phenoxy-ethylcarbamoyl)-methy...)
Affinity DataIC50: 385nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252319(Ethyl 2-oxo-2-{5-[(2-Phenoxy-ethylcarbamoyl)-methy...)
Affinity DataIC50: 204nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252319(Ethyl 2-oxo-2-{5-[(2-Phenoxy-ethylcarbamoyl)-methy...)
Affinity DataKi:  460nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed