BDBM50252500 6-(4-chlorobenzyl)-7-(3,3-dimethylbutyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL523336

SMILES CC(C)(C)CCn1c(Cc2ccc(Cl)cc2)cc2cnc(nc12)C#N

InChI Key InChIKey=YUICXLFAQWTQHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252500   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252500(6-(4-chlorobenzyl)-7-(3,3-dimethylbutyl)-7H-pyrrol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252500(6-(4-chlorobenzyl)-7-(3,3-dimethylbutyl)-7H-pyrrol...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed