BDBM50252579 (3,4-dichlorophenyl)(2-((dimethylamino)methyl)phenyl)methanone::CHEMBL453493

SMILES CN(C)Cc1ccccc1C(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=RYTIZBPXUHTIDS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252579   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252579((3,4-dichlorophenyl)(2-((dimethylamino)methyl)phen...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252579((3,4-dichlorophenyl)(2-((dimethylamino)methyl)phen...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252579((3,4-dichlorophenyl)(2-((dimethylamino)methyl)phen...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed