BDBM50252581 (2-(4-(methylthio)benzyl)phenyl)-N-methylmethanamine::CHEMBL492841

SMILES CNCc1ccccc1Cc1ccc(SC)cc1

InChI Key InChIKey=GVAGNJNCGNKLIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252581   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252581((2-(4-(methylthio)benzyl)phenyl)-N-methylmethanami...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252581((2-(4-(methylthio)benzyl)phenyl)-N-methylmethanami...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252581((2-(4-(methylthio)benzyl)phenyl)-N-methylmethanami...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed