BDBM50252634 CHEMBL493056::N-methyl(2-(4-(trifluoromethyl)phenylthio)phenyl)methanamine

SMILES CNCc1ccccc1Sc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=GJORZJNPTHLFPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252634   

LigandPNGBDBM50252634(N-methyl(2-(4-(trifluoromethyl)phenylthio)phenyl)m...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252634(N-methyl(2-(4-(trifluoromethyl)phenylthio)phenyl)m...)
Affinity DataIC50: 70nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252634(N-methyl(2-(4-(trifluoromethyl)phenylthio)phenyl)m...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed