BDBM50252638 (2-(3-chlorophenylthio)phenyl)-N,N-dimethylmethanamine::CHEMBL493263

SMILES CN(C)Cc1ccccc1Sc1cccc(Cl)c1

InChI Key InChIKey=IRKCYPUGOBXCFU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252638   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252638((2-(3-chlorophenylthio)phenyl)-N,N-dimethylmethana...)
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252638((2-(3-chlorophenylthio)phenyl)-N,N-dimethylmethana...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252638((2-(3-chlorophenylthio)phenyl)-N,N-dimethylmethana...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed