BDBM50252831 4-(p-Tolyl)spiro[chromene-2,4'-piperidine]::CHEMBL492448

SMILES Cc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12

InChI Key InChIKey=YDXKUUFNKUXOBE-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252831   

TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50252831(4-(p-Tolyl)spiro[chromene-2,4'-piperidine] | CHEMB...)
Affinity DataEC50:  810nMAssay Description:Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50252831(4-(p-Tolyl)spiro[chromene-2,4'-piperidine] | CHEMB...)
Affinity DataIC50: 462nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50252831(4-(p-Tolyl)spiro[chromene-2,4'-piperidine] | CHEMB...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed