BDBM50252832 4-(4-(Trifluoromethyl)phenyl)spiro [chromene-2,4'-piperidine]::CHEMBL492449

SMILES FC(F)(F)c1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12

InChI Key InChIKey=LWQXKZOHKORPRL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252832   

LigandPNGBDBM50252832(4-(4-(Trifluoromethyl)phenyl)spiro [chromene-2,4'-...)
Affinity DataIC50: 379nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50252832(4-(4-(Trifluoromethyl)phenyl)spiro [chromene-2,4'-...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50252832(4-(4-(Trifluoromethyl)phenyl)spiro [chromene-2,4'-...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed