BDBM50252952 CHEMBL495094::N,N-Diethyl-4-(7-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C1=CC2(CCNCC2)Oc2cc(O)ccc12

InChI Key InChIKey=VAPBXZGMTDKOBE-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252952   

TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50252952(N,N-Diethyl-4-(7-hydroxyspiro[chromene-2,4'-piperi...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50252952(N,N-Diethyl-4-(7-hydroxyspiro[chromene-2,4'-piperi...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50252952(N,N-Diethyl-4-(7-hydroxyspiro[chromene-2,4'-piperi...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed