BDBM50253320 2-(4-(4-Fluorophenyl)-5-(2-(3-methylbutan-2-ylamino)pyridin-4-yl)-1H-imidazol-2-ylthio)ethanol::CHEMBL524174

SMILES CC(C)C(C)Nc1cc(ccn1)-c1nc(SCCO)[nH]c1-c1ccc(F)cc1

InChI Key InChIKey=WWSBAAXRYHTMOX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253320   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University of TüBingen

Curated by ChEMBL
LigandPNGBDBM50253320(2-(4-(4-Fluorophenyl)-5-(2-(3-methylbutan-2-ylamin...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University of TüBingen

Curated by ChEMBL
LigandPNGBDBM50253320(2-(4-(4-Fluorophenyl)-5-(2-(3-methylbutan-2-ylamin...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50253320(2-(4-(4-Fluorophenyl)-5-(2-(3-methylbutan-2-ylamin...)
Affinity DataIC50: 181nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed