BDBM50253371 CHEMBL522172::N4-Isobutyl-6-(2-naphthalen-1-yl-ethyl)-N2-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine::N4-isobutyl-6-(2-(naphthalen-1-yl)ethyl)-N2-(naphthalen-1-ylmethyl)pyrimidine-2,4-diamine

SMILES CC(C)CNc1cc(CCc2cccc3ccccc23)nc(NCc2cccc3ccccc23)n1

InChI Key InChIKey=YTPZHZBEMLHUBF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253371   

TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253371(N4-Isobutyl-6-(2-naphthalen-1-yl-ethyl)-N2-naphtha...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253371(N4-Isobutyl-6-(2-naphthalen-1-yl-ethyl)-N2-naphtha...)
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity to ERalpha assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253371(N4-Isobutyl-6-(2-naphthalen-1-yl-ethyl)-N2-naphtha...)
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity to ERbeta assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed