BDBM50253613 2,4-Diamino-6-[N-(beta-naphthyl)-N-propylamino]quinazoline::CHEMBL492896

SMILES CCCN(Cc1ccc2ccccc2c1)c1ccc2nc(N)nc(N)c2c1

InChI Key InChIKey=KRNZWFKAPBBIRZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50253613   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253613(2,4-Diamino-6-[N-(beta-naphthyl)-N-propylamino]qui...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253613(2,4-Diamino-6-[N-(beta-naphthyl)-N-propylamino]qui...)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253613(2,4-Diamino-6-[N-(beta-naphthyl)-N-propylamino]qui...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253613(2,4-Diamino-6-[N-(beta-naphthyl)-N-propylamino]qui...)
Affinity DataIC50: 13nMAssay Description:Inhibition of Mycobacterium avium dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed