BDBM50253861 (+)-3-(4-Chlorophenyl)-N'-[(4-cyanophenyl)sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine::CHEMBL461855

SMILES Clc1ccc(cc1)C1=NN(C[C@H]1c1ccccc1)C(=N)NS(=O)(=O)c1ccc(cc1)C#N

InChI Key InChIKey=OQIBXTHHXDTIBJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50253861   

TargetCannabinoid receptor 1(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253861((+)-3-(4-Chlorophenyl)-N'-[(4-cyanophenyl)sulfonyl...)
Affinity DataIC50: 100nMAssay Description:Binding affinity to human CB1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253861((+)-3-(4-Chlorophenyl)-N'-[(4-cyanophenyl)sulfonyl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Binding affinity to human CB2 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253861((+)-3-(4-Chlorophenyl)-N'-[(4-cyanophenyl)sulfonyl...)
Affinity DataKi:  16.9nMAssay Description:Binding affinity to human CB1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253861((+)-3-(4-Chlorophenyl)-N'-[(4-cyanophenyl)sulfonyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to human CB2 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed