BDBM50253910 CHEMBL4089719

SMILES CCCCCOc1ccccc1C(=O)Nc1ncnc2[nH]cnc12

InChI Key InChIKey=XNCSRMKXGXDHTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253910   

TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253910(CHEMBL4089719)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253910(CHEMBL4089719)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BRD4 bromodomain 1 (49 to 170 residues) expressed in Escherichia coli using biotinylated peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed