BDBM50254011 CHEMBL6078355

SMILES Cn1c(=O)n([C@H]2CCC(=O)NC2=O)c2cccc(C#CCOC3CCN(C[C@H]4CC[C@H](n5cc(NC(=O)c6cnn7ccc(N8C[C@H]9C[C@@H]8CO9)nc67)c(C(F)F)n5)CC4)CC3)c21

InChI Key InChIKey=NQGKNAVUMAHSQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50254011   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Kymera Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254011BDBM50254011(CHEMBL6078355)
Affinity DataIC50: 12nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed