BDBM50254263 3-(2-Fluorobenzyl)-7-(5-methyl-2-thiazolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine::CHEMBL449469

SMILES Cc1cnc(s1)-c1nc(N)nc2n(Cc3ccccc3F)nnc12

InChI Key InChIKey=QAYSCRQTQREBQP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254263   

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254263(3-(2-Fluorobenzyl)-7-(5-methyl-2-thiazolyl)-3H-[1,...)
Affinity DataKi:  8.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254263(3-(2-Fluorobenzyl)-7-(5-methyl-2-thiazolyl)-3H-[1,...)
Affinity DataKi:  86nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254263(3-(2-Fluorobenzyl)-7-(5-methyl-2-thiazolyl)-3H-[1,...)
Affinity DataKi:  199nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254263(3-(2-Fluorobenzyl)-7-(5-methyl-2-thiazolyl)-3H-[1,...)
Affinity DataKi:  338nMAssay Description:Displacement of radioligand from human recombinant adenosine A3 receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed