BDBM50254385 CHEMBL4083680

SMILES FC(F)(F)Oc1ccc2c(n[nH]c2c1)-c1ccc(nc1)C#N

InChI Key InChIKey=LTWAIMIDHDTCGE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254385   

TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Pfizer

Curated by ChEMBL

LigandBDBM50254385(CHEMBL4083680)Copy SMILESCopy InChI

Affinity DataIC50: 271nMAssay Description:Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details Article
Copy BDB DOIPubMed
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50254385(CHEMBL4083680)Copy SMILESCopy InChI

Affinity DataIC50: 1.18E+3nMAssay Description:Antagonist activity at human TRPA1 by calcium flux based FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL