BDBM50254461 CHEMBL507546::N-(2-chlorobenzyl)-2-(N-(4-isobutoxy-3-methoxybenzyl)-4-(morpholinomethyl)phenylsulfonamido)acetamide

SMILES COc1cc(CN(CC(=O)NCc2ccccc2Cl)S(=O)(=O)c2ccc(CN3CCOCC3)cc2)ccc1OCC(C)C

InChI Key InChIKey=SLFXCPQWBOKOHY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254461   

TargetB1 bradykinin receptor(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50254461(N-(2-chlorobenzyl)-2-(N-(4-isobutoxy-3-methoxybenz...)
Affinity DataKi:  149nMAssay Description:Displacement of [3H]desArg from human B1 in human WI 38 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50254461(N-(2-chlorobenzyl)-2-(N-(4-isobutoxy-3-methoxybenz...)
Affinity DataKi:  463nMAssay Description:Antagonist activity at human cloned B1 receptor expressed in african green monkey COS7 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed