BDBM50254738 4-cyclopropyl-6-(2,5-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)nicotinamide::CHEMBL479628

SMILES Clc1ccc(Cl)c(Nc2cc(C3CC3)c(cn2)C(=O)NCC2CCOCC2)c1

InChI Key InChIKey=QKRGRWXDVSZBQO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254738   

TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254738(4-cyclopropyl-6-(2,5-dichlorophenylamino)-N-((tetr...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254738(4-cyclopropyl-6-(2,5-dichlorophenylamino)-N-((tetr...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254738(4-cyclopropyl-6-(2,5-dichlorophenylamino)-N-((tetr...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254738(4-cyclopropyl-6-(2,5-dichlorophenylamino)-N-((tetr...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of CYP1A2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254738(4-cyclopropyl-6-(2,5-dichlorophenylamino)-N-((tetr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed