BDBM50254761 5-amino-N-(2-((2,6-dichloro-N-(2-hydroxyethyl)benzamido)methyl)-3,3,3-trifluoro-2-hydroxypropyl)-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide::CHEMBL465451

SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)NCC(O)(CN(CCO)C(=O)c1c(Cl)cccc1Cl)C(F)(F)F

InChI Key InChIKey=UXDNAIXKDXHQMU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254761   

TargetCytochrome P450 2C9(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254761(5-amino-N-(2-((2,6-dichloro-N-(2-hydroxyethyl)benz...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254761(5-amino-N-(2-((2,6-dichloro-N-(2-hydroxyethyl)benz...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254761(5-amino-N-(2-((2,6-dichloro-N-(2-hydroxyethyl)benz...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254761(5-amino-N-(2-((2,6-dichloro-N-(2-hydroxyethyl)benz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254761(5-amino-N-(2-((2,6-dichloro-N-(2-hydroxyethyl)benz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed