BDBM50254773 CHEMBL3347696

SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(nn1)-c1ccccc1

InChI Key InChIKey=XFBZAGGLERWKQC-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50254773   

TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC8 using (FAM)-labeled acetylated peptide substrate at 1 uM incubated for 17 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC6 using (FAM)-labeled acetylated peptide substrate at 1 uM incubated for 17 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC2 using (FAM)-labeled acetylated peptide substrate at 1 uM incubated for 17 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC1 using (FAM)-labeled acetylated peptide substrate at 1 uM incubated for 17 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant HDAC3 using (FAM)-labeled acetylated peptide substrate at 1 uM incubated for 17 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC8 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC3 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 120nMAssay Description:Inhibition of His6-tagged HDAC3/SMRT (395 to 489 residues) (unknown origin) co-expressed in baculovirus infected sf9 cells using (FAM)-labeled acetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 120nMAssay Description:Inhibition of full length 6His-tagged HDAC3 (unknown origin)/SMRT (395 to 489 residues) (unknown origin) co-expressed in baculovirus infected Sf9 ins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC1 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC2 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC6 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50254773(CHEMBL3347696)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of C-terminal 6His-tagged HDAC10 (unknown origin) (632 to 669 residues) expressed in baculovirus infected Sf9 insect cells incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed