BDBM50254775 CHEMBL4094099

SMILES OC\C(=C/C(=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=YSDMFFBPTVKIEB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50254775   

TargetHistone deacetylase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254775(CHEMBL4094099)
Affinity DataIC50: 170nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells after 1 hr in presence of acetylated l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254775(CHEMBL4094099)
Affinity DataIC50: 170nMAssay Description:Inhibition of HDAC2 (unknown origin) measured after 24 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254775(CHEMBL4094099)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells after 1 hr in presence of acetyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254775(CHEMBL4094099)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) measured after 24 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254775(CHEMBL4094099)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) measured after 1 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254775(CHEMBL4094099)
Affinity DataIC50: 9.19E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) measured after 1 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254775(CHEMBL4094099)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 co-expressed in baculovirus infected Sf9 insect cells a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed