BDBM50254776 CHEMBL2132717

SMILES C[C@H](CO)N1C[C@H](C)[C@H](CN(C)Cc2ccc(cc2)C(=O)Nc2ccccc2N)Oc2ccc(cc2CC1=O)N(C)C

InChI Key InChIKey=ZBLCOVKAEUNWGN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254776   

TargetHistone deacetylase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254776(CHEMBL2132717)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells preincubated for 3 hrs follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254776(CHEMBL2132717)
Affinity DataIC50: 560nMAssay Description:Inhibition of human full length C-terminal His/FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells preincubated for 3 hrs followed by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254776(CHEMBL2132717)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) co-expressed in baculovirus infec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed