BDBM50254779 CHEMBL4061025

SMILES C\C=C1/NC(=O)[C@H](CS)NC(=O)[C@H](NC(=O)C[C@H](OC(=O)[C@@H](NC1=O)C(C)C)\C=C\CS)C(C)C

InChI Key InChIKey=KEFLLVVROWXXSJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254779   

TargetHistone deacetylase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254779(CHEMBL4061025)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human HDAC1 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254779(CHEMBL4061025)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC2 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254779(CHEMBL4061025)
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC4 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM50254779(CHEMBL4061025)
Affinity DataIC50: 790nMAssay Description:Inhibition of human HDAC6 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2019
Entry Details Article
PubMed