BDBM50254975 1,3-Dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione::CHEMBL480599

SMILES Cn1c2nc3[nH]c(cn3c2c(=O)n(C)c1=O)-c1ccccc1

InChI Key InChIKey=UKMQTJFZUOZSRV-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254975   

TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254975(1,3-Dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254975(1,3-Dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]MRE3008F20 from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254975(1,3-Dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254975(1,3-Dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human cloned adenosine A2B cells expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed