BDBM50254976 1,3,7-Trimethyl-1H,8H-imidazo[2,1-f]purine-2,4-dione::CHEMBL480529

SMILES Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)[nH]1

InChI Key InChIKey=UCRWKJWWUYKFAC-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254976   

TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254976(1,3,7-Trimethyl-1H,8H-imidazo[2,1-f]purine-2,4-dio...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254976(1,3,7-Trimethyl-1H,8H-imidazo[2,1-f]purine-2,4-dio...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]MRE3008F20 from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254976(1,3,7-Trimethyl-1H,8H-imidazo[2,1-f]purine-2,4-dio...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254976(1,3,7-Trimethyl-1H,8H-imidazo[2,1-f]purine-2,4-dio...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human cloned adenosine A2B cells expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed