BDBM50255166 CHEMBL4098331

SMILES NC(=O)c1cnc(N(CCc2ccccc2)[C@H]2CCCNC2)c2cc(sc12)-c1ccccc1

InChI Key InChIKey=NEWBEAKFVLKLNW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255166   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50255166(CHEMBL4098331)Copy SMILESCopy InChI

Affinity DataIC50: 660nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/12/2019
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50255166(CHEMBL4098331)Copy SMILESCopy InChI

Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/12/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL