BDBM50255367 2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitrile::CHEMBL479835

SMILES COc1ccc(CN(C)C)c(c1)-c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N

InChI Key InChIKey=ZZARJEJPLRJJQO-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50255367   

TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human full length PKCthetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human full length PKCdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human full length PKCbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of human full length PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255367(2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4...)
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibition of human full length PKCetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed