BDBM50255418 4-(2,4-difluorophenylamino)-6,7-dimethoxyquinoline-3-carboxamide::CHEMBL479847

SMILES COc1cc2ncc(C(N)=O)c(Nc3ccc(F)cc3F)c2cc1OC

InChI Key InChIKey=UVENYMMUFIZZMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255418   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255418(4-(2,4-difluorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255418(4-(2,4-difluorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed