BDBM50255514 4-(3-chloro-4-fluorophenylamino)-7-(2-(dimethylamino)ethoxy)-6-methoxyquinoline-3-carboxamide::CHEMBL517069

SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cc1OCCN(C)C)C(N)=O

InChI Key InChIKey=AZNVGEUTVWCXBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255514   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255514(4-(3-chloro-4-fluorophenylamino)-7-(2-(dimethylami...)
Affinity DataIC50: 12nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed