BDBM50255586 4-(3-chloro-4-fluorophenylamino)-7-(2-((2-hydroxyethyl)(methyl)amino)ethoxy)-6-methoxyquinoline-3-carboxamide::CHEMBL481230

SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cc1OCCN(C)CCO)C(N)=O

InChI Key InChIKey=LMFNTPHSFMIWNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255586   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255586(4-(3-chloro-4-fluorophenylamino)-7-(2-((2-hydroxye...)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed