BDBM50255625 CHEMBL4070714

SMILES CCCCCCCCCCCC(=O)N[C@H]1[C@@H](OP(O)([O-])=O)O[C@H](CO)[C@@H](OP(O)([O-])=O)[C@@H]1OC(=O)CCCCCCCCCCC

InChI Key InChIKey=WNTDQZSFFDALOD-UHFFFAOYSA-L

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255625   

TargetToll-like receptor 4(Human)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255625(CHEMBL4070714)
Affinity DataIC50: 630nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Human)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255625(CHEMBL4070714)
Affinity DataKd:  1.40E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255625(CHEMBL4070714)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at human TLR4 expressed in mouse RAW blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP producti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed