BDBM50255681 CHEMBL473448::N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-(4-methyl-pyridine-3-sulfonylamino)-benzamide

SMILES CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC1(C)CCCC1)NC(=O)c1ccc(NS(=O)(=O)c2cnccc2C)cc1

InChI Key InChIKey=DCDFVKDUIGKXRF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255681   

TargetCathepsin S(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50255681(N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamo...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50255681(N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamo...)
Affinity DataKi:  260nMAssay Description:Inhibition of human recombinant cathepsin K expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50255681(N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamo...)
Affinity DataKi:  8.70E+3nMAssay Description:Inhibition of human cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed