BDBM50255841 CHEMBL517377::N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-methoxybenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide

SMILES COc1cccc(CN2C(=O)CC3(C)CCCC(\C=C\C(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)=C23)c1

InChI Key InChIKey=OIDRWTDKINPYNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255841   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255841(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-meth...)
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255841(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-meth...)
Affinity DataIC50: 6.10E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255841(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-meth...)
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed