BDBM50255892 CHEMBL481501::trans-4-(((2S,4S)-4-fluoro-1-(2-(2-(o-tolylamino)benzo[d]oxazol-6-yl)acetyl)pyrrolidin-2-yl)methoxy)cyclohexanecarboxylic acid::trans-4-[[2-(2-Methylphenylamino)-6-benzoxazolylacetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid

SMILES Cc1ccccc1Nc1nc2ccc(CC(=O)N3C[C@@H](F)C[C@H]3CO[C@H]3CC[C@@H](CC3)C(O)=O)cc2o1

InChI Key InChIKey=CTRIJHIVZHRDHX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255892   

TargetIntegrin alpha-4(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255892(trans-4-(((2S,4S)-4-fluoro-1-(2-(2-(o-tolylamino)b...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255892(trans-4-(((2S,4S)-4-fluoro-1-(2-(2-(o-tolylamino)b...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells by fluorimetric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255892(trans-4-(((2S,4S)-4-fluoro-1-(2-(2-(o-tolylamino)b...)
Affinity DataIC50: 45nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells in presence of 3% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed