BDBM50256128 (2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid::(trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid::CHEMBL449993

SMILES CCCCCCCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O

InChI Key InChIKey=VCWLZDVWHQVAJU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50256128   

TargetFatty acid synthase(Rat)
Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty acid synthase(Rat)
Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of FASN in human A375 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of human recombinant FASN thioesterase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed