BDBM50256213 CHEMBL4082835

SMILES C[C@@H]1CN(CCN1C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1)c1ncc(cn1)C(F)(F)F

InChI Key InChIKey=ZTRZRVOBPDZZDL-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256213   

TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Shionogi

Curated by ChEMBL

LigandBDBM50256213(CHEMBL4082835)Copy SMILESCopy InChI

Affinity DataIC50: 62nMAssay Description:Antagonist activity at recombinant rat TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins fo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/9/2020
Entry Details Article
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TargetTransient receptor potential cation channel subfamily V member 4(Human)
Shionogi

Curated by ChEMBL

LigandBDBM50256213(CHEMBL4082835)Copy SMILESCopy InChI

Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at recombinant human TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/9/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL