BDBM50256371 CHEMBL4067320

SMILES Cc1[nH]c(c2CCNC(=O)c12)-c1cc(NS(C)(=O)=O)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=MLNOGJLNUKUYDQ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256371   

TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50256371(CHEMBL4067320)
Affinity DataEC50:  420nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50256371(CHEMBL4067320)
Affinity DataKi:  84nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2019
Entry Details Article
PubMed