BDBM50256946 (S)-benzyl 1-(4-tert-butylthiazol-2-ylamino)-1-oxo-6-(sulfamoylamino)hexan-2-ylcarbamate::CHEMBL475862

SMILES CC(C)(C)c1csc(NC(=O)[C@H](CCCCNS(N)(=O)=O)NC(=O)OCc2ccccc2)n1

InChI Key InChIKey=BBDWOHDPFZUDCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256946   

TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256946((S)-benzyl 1-(4-tert-butylthiazol-2-ylamino)-1-oxo...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256946((S)-benzyl 1-(4-tert-butylthiazol-2-ylamino)-1-oxo...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed