BDBM50257047 (S)-benzyl 1-(4-(4-isopropylphenyl)thiazol-2-ylamino)-1-oxo-6-(sulfamoylamino)hexan-2-ylcarbamate::CHEMBL516399

SMILES CC(C)c1ccc(cc1)-c1csc(NC(=O)[C@H](CCCCNS(N)(=O)=O)NC(=O)OCc2ccccc2)n1

InChI Key InChIKey=IVFPOHHSUTWRCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257047   

TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257047((S)-benzyl 1-(4-(4-isopropylphenyl)thiazol-2-ylami...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257047((S)-benzyl 1-(4-(4-isopropylphenyl)thiazol-2-ylami...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed