BDBM50257049 (S)-4-chlorobenzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(sulfamoylamino)hexan-2-ylcarbamate::CHEMBL516218

SMILES NS(=O)(=O)NCCCC[C@H](NC(=O)OCc1ccc(Cl)cc1)C(=O)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=SMAZYQRVLCYYEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257049   

TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257049((S)-4-chlorobenzyl 1-oxo-1-(4-phenylthiazol-2-ylam...)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257049((S)-4-chlorobenzyl 1-oxo-1-(4-phenylthiazol-2-ylam...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed