BDBM50257130 (S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetamido)-N-(4-phenylthiazol-2-yl)-6-(sulfamoylamino)hexanamide::CHEMBL494124

SMILES COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCNS(N)(=O)=O)C(=O)Nc3nc(cs3)-c3ccccc3)c2c1

InChI Key InChIKey=UMWRGESNBMPCQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257130   

TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257130((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257130((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed