BDBM50257132 (S)-benzyl 1-(2-phenylthiazol-4-yl)-5-(sulfamoylamino)pentylcarbamate::CHEMBL492312

SMILES NS(=O)(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)c1csc(n1)-c1ccccc1

InChI Key InChIKey=KYMADELXCHTVCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257132   

TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257132((S)-benzyl 1-(2-phenylthiazol-4-yl)-5-(sulfamoylam...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257132((S)-benzyl 1-(2-phenylthiazol-4-yl)-5-(sulfamoylam...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed